Angiogenesis and Its Therapeutic Implication 6. Angiogenesis in the Progression of Lung Cancer
نویسندگان
چکیده
منابع مشابه
Angiogenesis in Control and Progression of Lung Cancer
Pro-angiogenic endothelial cell signal transduction has evolved as a target of choice in cancer research being indispensable for neovascularization and hence survival of solid tumors [1]. Tumor cells express several target features associated with their angiogenic activation that could be explored as specific targets which may cause either the destruction of existing tumor vasculature [2-5] or ...
متن کاملAngiogenesis and Its Therapeutic Opportunities
Angiogenesis plays critical roles in human physiology that range from reproduction and fetal growth to wound healing and tissue repair. The sophisticated multistep process is tightly regulated in a spatial and temporal manner by "on-off switch signals" between angiogenic factors, extracellular matrix components, and endothelial cells. Uncontrolled angiogenesis may lead to several angiogenic dis...
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چکیده: سرطان پستان دومین عامل مرگ مرتبط با سرطان در خانم ها است. از آنجا که سرطان پستان یک تومور وابسته به هورمون است، می تواند توسط وضعیت هورمون های استروئیدی شامل استروژن و پروژسترون تنظیم شود. استروژن نقش مهمی در توسعه و پیشرفت سرطان پستان ایفا می کند و تاثیر خود را روی بیان ژن های هدف از طریق گیرنده های استروژن اعمال می کند. اما گروه دیگری از گیرنده های هسته ای به نام گیرنده های مرتبط به ا...
15 صفحه اولAngiogenesis and Lung Cancer
Tumors acquire blood vessels by co-option of neighboring vessels from sprouting or intus‐ suscepted microvascular growth and by vasculogenesis from endothelial precursor cells [2]. In most solid tumors the newly formed vessels are plagued by structural and functional ab‐ normalities due to the sustained and excessive exposure to angiogenic factors produced by the tumor [3]. As a result of this,...
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Angiogenesis or formation of new blood vessels from preexisting vasculature is a key process in some physiological conditions such as wound healing, growth, and action of female reproductive organs. Moreover, disturbance of the mechanisms of physiological angiogenesis has a role in pathogenesis of some diseases in the form of overproliferation of blood vessels such as cancers, psoriasis, arthri...
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ژورنال
عنوان ژورنال: Internal Medicine
سال: 2003
ISSN: 0918-2918,1349-7235
DOI: 10.2169/internalmedicine.42.305